Units to mL Converter (and mL to Units) for Insulin Syringes
Written by Kashif Khan, who builds and maintains this site and is not a clinician. Every figure links to its primary source.
100 units = 1 mL on a U-100 insulin syringe, so 10 units is 0.1 mL, 50 units is 0.5 mL and 1 mL is 100 units. Unlike mg to units, this conversion is fixed — both sides measure volume. The only thing that changes it is the scale printed on the barrel.
mL to units table
Units = mL × the U number. Figures marked “over capacity” are more than the largest barrel on that scale holds.
Units to mL table
mL = units ÷ the U number.
Which syringe holds how much
U-100 insulin syringes come in three sizes, and the printed steps differ — the 1 mL barrel is usually marked every 2 units, so odd numbers fall between lines.
- 0.3 mL "30 unit" (U-100) — holds 30 units, marked every 1 unit
- 0.3 mL half-unit (U-100) — holds 30 units, marked every 0.5 units
- 0.5 mL "50 unit" (U-100) — holds 50 units, marked every 1 unit
- 1 mL "100 unit" (U-100) — holds 100 units, marked every 2 units
- 1 mL U-40 (veterinary) — holds 40 units, marked every 1 unit
- 1 mL U-500 — holds 500 units, marked every 1 unit
Anything over 1 mL — 2 mL, 2.5 mL, 3 mL — is not an insulin-syringe volume at all. It is drawn with a luer syringe graduated in millilitres, which is also what you use to add bacteriostatic water to a vial.
When you need milligrams, not millilitres
mL to units tells you where to stop the plunger. How much drug that volume holds depends on your vial concentration — use mg to units or mcg to units for that, or the peptide calculator to do the whole thing from your own vial.
Common questions
Sources
Every number on this page comes from one of the documents below. Where no reliable source exists, the page says so instead of filling the gap.
- GuidelineInternational Organization for Standardization· 2016-03ISO 8537:2016 — Sterile single-use syringes, with or without needle, for insulin (scope and requirements; full text not public)
- RegulatorUS Code of Federal Regulations / FDA21 CFR 522.1160 — Insulin (animal drugs): 40 international units (IU) per millilitre
- GuidelineInstitute for Safe Medication PracticesISMP safety alerts on U-500 and U-100 insulin syringe confusion
- RegulatorFDA / CDRH· 2016-07510(k) K151870 — U-500 insulin syringe, substantial equivalence determination (cleared 8 July 2016)
- FDA labelFDA Center for Veterinary Medicine / DailyMedVETSULIN (porcine insulin zinc suspension) 40 IU/mL — FDA CVM-approved label and owner information sheet
- Published studyCase Reports in Endocrinology 2019;2019:7916435· 2019Barrera F, Murvelashvili N. Poorly controlled type 3c diabetes due to use of veterinarian insulin syringes
- Published studyJournal of Family Medicine and Primary Care 2017;6(4):724–729· 2017Chowdhury S, Chakraborty PP. Errors of insulin therapy: real-life experiences from developing world